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Francesco Della Valle, PhD

Francesco Della Valle, PhD

Alumni

Postdoctoral Researcher

Alumni

Location:

3204_WS012

Social Profile:

Biography

Current Job:

Senior research scientist in  Juan Carlos Belmonte  lab at San Diego Institute of Science PHD ( Altos lab )

Research Interests

L1 transposable elements analysis in progeria syndrome and cellular senescence.


Selected Publications

  • Francesco Della Valle1, Pradeep Reddy1, Mako Yamamoto Tsui, Javier Prieto Martinez, Alejandro Ocampo, Mirko Celii, Arianna Mangiavacchi, Leila Abassi, Juan Carlos Izpisua Belmonte & Valerio Orlando“L1 RNA knockdown averts heterochromatin loss and premature aging phenotypes”
  • Nadine Hosny El Said1*, Francesco Della Valle1*, Peng Liu1, Andreu Paytuví-Gallart2, Sabir Adroub1, Juliette Gimenez3, Valerio Orlando1+. PRC2-EZH1 requires Malat1 interaction for oxidative stress-dependent H3K27me3 remodeling in myotubes. Cell Death and Differentiation submitted 2021
  • Francesco Della Valle1, Manjula P. Thimma1, Massimiliano Caiazzo2,3,4, Salvatore Pulcrano4, Sabir A. Adroub1, Peng Liu1, Gregorio A. Lobato1 , Vania Broccoli4, Valerio Orlando1. Transdifferentiation of Mouse Embryonic Fibroblasts into Dopaminergic Neurons Reactivates LINE-1 Repetitive Elements. Stem cell Reports 2020
  • Beatrice Bodega, Federica Marasca, Valeria Ranzani, Alessandro Cherubini, Francesco Della Valle, Maria Victoria Neguembor, Michel Wassef, Alessio Zippo, Chiara Lanzuolo, Massimiliano Pagani, Valerio Orlando. A cytosolic Ezh1 isoform modulates a PRC2-Ezh1 epigenetic adaptive response in postmitotic cells. Nature structure and molecular biology, 2017
  • Corsetti V, Florenzano F, Atlante A, Bobba A, Ciotti MT, Natale F, Della Valle F, Borreca A, Manca A, Meli G, Ferraina C, Feligioni M, D'Aguanno S, Bussani R, Ammassari-Teule M, Nicolin V, Calissano P, Amadoro G. NH2-truncated human tau induces deregulated mitophagy in neurons by aberrant recruitment of Parkin and UCHL-1: implications in Alzheimer's disease. Hum Mol Genet. 2015
  • Borreca A, Latina V, Corsetti V, Middie S, Piccinin S, Della Valle F, Bussani R, Ammassari-Teule M, Nisticò R, Calissano P, Amador G. AD-Related N-Terminal Truncated Tau Is Sufficient to Recapitulate In Vivo the Early Perturbations of Human Neuropathology: Implications for Immunotherapy. Mol Neurobiol. 2018 

Education

  • 2005  High school diploma, scientific studies, Francesco Selmi institute with a score of 96/100
  • 2010 Master's degree in medical and Pharmaceutical Biotechnology, University of Modena and Reggio Emilia with  110/110 cum laude.Thesis title: “Transcription factors Crx and Nrl: induction of transdifferentiation of  661w neuronal cell line into photoreceptors.”
  • 2015  Ph.D. in Neuroscience, University of Tor Vergata. Rome, Itali -Thesis title: Line1 repetitive elements dynamic occurs in  neural transdifferentiation                                                                   and muscular cell differentiation
  • 2011 FELASA certificate cat.B : LABORATORY ANIMAL SCIENCE     




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