Organoids — Preclinical Models of Human Disease

by Mo Li, Ph.D., Juan C. Izpisua Belmonte, Ph.D.
Year: 2019

Extra Information

N Engl J Med 2019; 380:569-579 DOI: 10.1056/NEJMra1806175


An organoid is a three-dimensional construct composed of multiple cell types that originates from stem cells through self-organization and can simulate the architecture and functionality of native organs. This article reviews the common platforms of organoid technology and its application.