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Zymo Research Visited KAUST


Zymo Research Corporation was founded by Larry Jia in 1994. The company started its home base in Orange, CA, manufacturing products for DNA and RNA extraction and purification and other specialty products for E. coli and yeast based research. Since then, it has expanded its product offerings to include tools for Epigenetics research. As of December 2010, the privately held company has relocated its headquartered operations to Irvine, CA. In 2009, Zymo Research Europe was established in Freiburg, Germany.
Zymo Research offers from their Epigenetics line-up products for CpG methylation detection and quantitation. Many of these products exploit the bisulfite conversion approach, wherein unmethylated cytosine is converted to uracil, allowing for downstream sequencing analysis. The company also offers polymerases optimized for PCR analysis of bisulfite-converted DNA, as well as antibodies for IP-based epigenetics research.
In addition to their methylation portfolio, Zymo Research recently began to offer product lines for analysis of 5-hydroxymethylcytosine. In late 2010, the company became the first to offer a kit for locus specific 5-hydroxymethylcytosine detection (protection, digestion, amplification).
Included in the company┬╣s epigenetics portfolio are kits for nucleosomal DNA purification, chromatin immunoprecipitation, and small RNA isolation.